#animalmodel

Building a brain map of alcohol dependence.

Jan 14, 20203 min read

Building a brain map of alcohol dependence.

This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....

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Treating opioid use disorder one rat at a time.

Olivier George

Jan 14, 20201 min read

Treating opioid use disorder one rat at a time.

This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....

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Identification of a new target that reduces excessive opioid use in dependent individuals.

Olivier George

Jan 13, 20202 min read

Identification of a new target that reduces excessive opioid use in dependent individuals.

This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...

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Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence

Olivier George

Mar 26, 20193 min read

Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence

This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire...

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An Enzymatic Approach for the Treatment of Nicotine Addiction

Olivier George

Oct 17, 20184 min read

An Enzymatic Approach for the Treatment of Nicotine Addiction

The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of...

179 views0 comments

Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.

Olivier George

Oct 14, 20183 min read

Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.

The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and...

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Identification of the cellular mechanisms of drug and nicotine addiction.

Olivier George

Jul 5, 20182 min read

Identification of the cellular mechanisms of drug and nicotine addiction.

The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible...

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A novel target for the treatment of alcohol use disorder.

Olivier George

Jul 5, 20181 min read

A novel target for the treatment of alcohol use disorder.

Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical...

142 views0 comments

An enzymatic advance in nicotine cessation therapy.

Olivier George

Jan 9, 20181 min read

An enzymatic advance in nicotine cessation therapy.

The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme...

153 views0 comments

Alcohol binge-drinking facilitates the transition to dependence, but regular drinking may be almost

Olivier George

Aug 26, 20172 min read

Alcohol binge-drinking facilitates the transition to dependence, but regular drinking may be almost

The George lab published a new study providing preclinical evidence that several months of alcohol binge-like drinking facilitates the...

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Cortical and Amygdalar Neuronal Ensembles in Alcohol Seeking, Drinking and Withdrawal

Olivier George

May 27, 20171 min read

Cortical and Amygdalar Neuronal Ensembles in Alcohol Seeking, Drinking and Withdrawal

The George lab published a new invited review in collaboration with Dr. Bruce Hope at the National Institute on Drugs of Abuse (NIDA) on...

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Voluntary vaping alcohol produces alcohol dependence in rats.

Olivier George

Apr 11, 20173 min read

Voluntary vaping alcohol produces alcohol dependence in rats.

The George lab published a new study providing preclinical evidence that self-administration of alcohol vapor produces alcohol dependence...

184 views0 comments

New paper published: Nicotine facilitates the transition to alcohol dependence through dysfunction o

Olivier George

Apr 14, 20153 min read

New paper published: Nicotine facilitates the transition to alcohol dependence through dysfunction o

LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do...

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New paper published: Finding new ways to treat methamphetamine dependence.

Olivier George

Mar 12, 20153 min read

New paper published: Finding new ways to treat methamphetamine dependence.

LA JOLLA, CA – March 11, 2015 – Methamphetamine abuse and dependence is a major issue in the US. More than 1 million people used...

10 views0 comments

New paper published by the George Lab: Identification of a new type of neurons that contributes to n

Olivier George

Nov 17, 20144 min read

New paper published by the George Lab: Identification of a new type of neurons that contributes to n

TSRI Researchers Discover New Type of Neuron that Plays Key Role in Nicotine Addiction LA JOLLA, CA – November 17, 2014 – For decades,...

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Postdoctoral position available in the lab
UPDATE: position has been filled.

Olivier George

Aug 15, 20141 min read

Postdoctoral position available in the lab UPDATE: position has been filled.

A postdoctoral position will be available in the lab in a near future: Succesful applicants will receive training under support from the...

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Smoking may produce excessive immature neurons

Olivier George

Aug 4, 20141 min read

Smoking may produce excessive immature neurons

Latest paper published: Nicotine dependence increases the number of immature neurons in the hippocampus. It was believed that nicotine...

198 views0 comments

Olivier George

Jul 25, 20141 min read

Characterization of HIV rats

Latest paper published: A neuroanatomical, genetical, and cognitive characterization of HIV rats. This paper (link to PDF) validates the...

8 views0 comments

Olivier George

Jun 11, 20141 min read

How rats order a Martini

This video shows how rats vocalize in anticipation of access to alcohol. They produce sounds that the human ear can't process, but if you...

7 views0 comments

Decreased, not increased phasic dopamine release predict cocaine dependence

Olivier George

Apr 25, 20141 min read

Decreased, not increased phasic dopamine release predict cocaine dependence

This is to me one of the most important paper of the decade in the addiction field. It kicks to the curb both the incentive sensitization...

19 views0 comments

Upcoming Events

Gordon Research Conference: Alcohol and the Nervous System

Dr. George will be speaking. "What's Driving Escalation of Alcohol Drinking? Evidence in Favor of the Crystallization Hypothesis"

Developing a Clearer Vision of the Integrated Neural Actions of Ethanol

Match 1-6, 2020

Galveston, TX

Click Here

Gordon Research Conference: Addiction Research: From Molecules to Circuits to Treatment

Dr. George will be speaking. "The Escalation Model of Drug Addiction"

Addiction Research: From Molecules to Circuits to Treatment

August 16-21, 2020

Newry, ME

Click Here

New Mexico Medical Cannabis Conference

Dr. George will be speaking. "Effect of CBD on Nicotine Dependence"

March 15, 2020

Albuquerque , NM

Click Here

Research Society on Alcoholism

Dr. Kimbrough will be speaking. "Brain wide neural activation in animal models of alcohol abuse and dependence"

June 22-26th, 2019

Minneapolis, Minnesota

Click Here

Lisbon Addiction 2019

Dr. George will be speaking. "From big data to small pathways: multilevel mechanisms of addiction-like behaviors."

October 23-25th, 2019

Lisbon, Portugal

International Behavioral Neuroscience Society

Dr. George will be speaking. "From big data to small pathways: multilevel mechanisms of addiction-like behaviors."

June 23-27th, 2019

Cairns, Australia

European Winter Conference on Brain Research

Dr. George will be speaking. "From big data to small pathways: multilevel mechanisms of addiction-like behaviors."

March 17-22th, 2019

Les Arcs, France

NeuroHIV Emerging Issues and Substance Abuse Joint Colloquium Nov 22-24th 2018

Dr. George will be speaking on "Identification of novel targets for cocaine and opioid use disorders using heterogeneous stock rats."

Society For Neuroscience Nov 3-7th 2018

Come see us at SFN in San Diego

Nov 3-7th, 2018

Outreach: Science Saturday Nov 17th 2018

Dr. George will be speaking on “Drug Wars: Episode IV – A New Hope”

Finding new therapies to fight drug addiction: The lecture will describe the effects of drugs on the brain, including alcohol, nicotine, cocaine and opioids; why some people, but not others, develop an addiction; and highlight new therapeutic strategies to fight addiction.

Scripps Research scientists and researchers bring the excitement and passion of research to middle and high school students. Every lecture highlights the cutting-edge research occurring at The Scripps Research Institute and provides a window into the life of a scientist.

Contact the Office of Educational Outreach

"Drug Addiction & Mental Disorders" & "Impulse Control Disorders"

Dr. George is teaching PSYC 179 and PSYC188 at UCSD in Summer and Fall 2018

Summer and Fall 2018

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Addiction Research Laboratory at UCSD

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