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May 26, 20202 min read
The Role of Corticotrophin Releasing Factor in Alcohol and Nicotine Addiction
Our newest review, “Role of CRF in Alcohol and Nicotine Addiction” was recently published in a special collection on "The Role of...
212 views0 comments
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May 26, 20203 min read
Depletion of the Microbiome Changes How the Brain Responds to Opioids
Substance use disorders are complex. Genetics, environment, and exposure all play a role in drug use. Recently, there has been evidence...
266 views0 comments
Olivier George
Jan 14, 20203 min read
Building a brain map of alcohol dependence.
This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....
242 views0 comments
Olivier George
Jan 14, 20201 min read
Treating opioid use disorder one rat at a time.
This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....
76 views0 comments
Olivier George
Jan 13, 20202 min read
Identification of a new target that reduces excessive opioid use in dependent individuals.
This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...
68 views0 comments
Olivier George
Mar 26, 20193 min read
Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence
This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire...
119 views0 comments
Olivier George
Oct 17, 20184 min read
An Enzymatic Approach for the Treatment of Nicotine Addiction
The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of...
181 views0 comments
Olivier George
Oct 14, 20183 min read
Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.
The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and...
100 views0 comments
Olivier George
Jul 5, 20182 min read
Identification of the cellular mechanisms of drug and nicotine addiction.
The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible...
97 views0 comments
Olivier George
Jul 5, 20181 min read
A novel target for the treatment of alcohol use disorder.
Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical...
142 views0 comments
Olivier George
Jul 2, 20181 min read
It is time to put the patient at the center of addiction treatments.
Dr. George published a new review article in collaboration with Dr. Koob that argues that characterization of the neuropsychological...
18 views0 comments
Olivier George
Jan 9, 20181 min read
An enzymatic advance in nicotine cessation therapy.
The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme...
153 views0 comments
Olivier George
Aug 26, 20172 min read
Alcohol binge-drinking facilitates the transition to dependence, but regular drinking may be almost
The George lab published a new study providing preclinical evidence that several months of alcohol binge-like drinking facilitates the...
105 views0 comments
Olivier George
May 27, 20171 min read
Cortical and Amygdalar Neuronal Ensembles in Alcohol Seeking, Drinking and Withdrawal
The George lab published a new invited review in collaboration with Dr. Bruce Hope at the National Institute on Drugs of Abuse (NIDA) on...
114 views0 comments
Olivier George
Apr 11, 20173 min read
Voluntary vaping alcohol produces alcohol dependence in rats.
The George lab published a new study providing preclinical evidence that self-administration of alcohol vapor produces alcohol dependence...
184 views0 comments
Olivier George
Feb 1, 20171 min read
Deep brain stimulation reduces the compulsion to take heroin.
The George lab published a novel study providing preclinical evidence that deep brain stimulation can decrease the motivation for heroin...
116 views0 comments
Olivier George
Sep 7, 20161 min read
Reversal of alcohol dependence by pharmacogenetic manipulation of a neuronal ensemble.
The George lab published a novel study identifying a neuronal network that may be critical for alcoholism. This preclinical study lead by...
124 views0 comments
Olivier George
Dec 29, 20151 min read
Novel transgenic rat to open the doors of the brain stress system.
The George lab in collaboration with the Messing lab (University of Texas at Austin), the Janak lab (University of San Francisco), and...
53 views0 comments
